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Oral GLP-1 RA are under development to improve convenience, acceptance, and adherence and may provide an additional option to support obesity management. Additionally, a large pipeline of entero-pancreatic hormone-based pharmacotherapies is under development, with the aim to enhance and/or compliment...
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GLP-1 receptor agonists and SGLT-2is were found to exert striking benefits on the heart, liver, kidney, and even the brain [34,35,36,37,38,39,40]. Emerging research indicates that these benefits are conferred by pleiotropic mechanisms, that is, pathways distinct from those involved in gluc...
explore the link between gut dysbiosis and cognitive decline in CKD, highlighting how uremic toxins, short-chain fatty acids, and hormones such as GLP-1 and CCK affect brain processes, including mood regulation and blood–brain barrier integrity. They suggest that diet, prebiotics, and probiotics ...
GLP-1 is the satiety hormone mimicked by Ozempic. Boundaries 4 Min Read How to Build Better Boundaries Setting boundaries is essential to continue serving the needs of others at the highest level. Most PopularFind Counselling Get the help you need from a counsellor near you–a...
Introduction The number of people suffering from type 2 diabetes (T2D) and its complications is on the rise; and, thus continues to expand the market for pharmacologic agents targeting the disease. At present, only the glucagon-like peptide 1 receptor agonists (GLP-1 RA) and sodium-glucose ...
experienced the greatest reductions in LDL-C, total cholesterol, and TGs, and the greatest increases in HDL-C [67]. The first placebo-controlled, GLP-1 RA, CV safety trial with lixisenatide (Evaluation of Lixisenatide in Acute Coronary Syndrome [ELIXA] trial) showed no specific ASCVD benefit ...
Pharmacy: Specialty pharmacy and GLP-1s continue to drive segment growth The pharmacy market has undergone major changes in recent years, including a rapidly evolving regulatory environment, formation of new partnerships across the value chain, and growing demand for GLP-1 agon...
GLP-1 RA, Thiazolidinedione Combo Linked to Lower Mortality in Type 2 Diabetes Pearl Steinzor A real-world study finds cardiovascular and survival benefits from dual therapy in patients with type 2 diabetes. February 18th 2025 Varied Access: The Pharmacogenetic Testing Coverage Divide Brooke McCormick...