Today, PD is exclusively treated symptomatically, mainly by dopaminergic stimulation, while efforts to modify disease progression could not yet be translated to the clinics. New formulations of approved drugs and treatment options of motor fluctuations in advanced stages accompanied by telehealth ...
Hart N, McGowan J, Minati L, Critchley HD (2013) Emotional regulation and bodily sensation: interoceptive awareness is intact in borderline personality disorder. J Personal Disord 27:506–518. https://doi.org/10.1521/pedi_2012_26_049 Article Google Scholar Hartmann EM, Handwerker HO, Forster...
Finally, the combination of genetic sex and gonadal hormones alone can produce a plethora of points at which subtle differences promote dramatic trajectory changes in development. An example of this is from Catherine Dulac's group in which they investigated the genetics of sex differences in the ...
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31,34 Olesen149 recently admonished: "It is time for many practitioners of medicine to change their views and to acknowledge that migraine is a neurobiologic, not a psychogenic disorder." Even the most prominent skeptics would agree that millions of people have widespread, idiopathic chronic pain...
We then review existing genetic rodent models with disruptions in ASD candidate genes, and we map their phenotypes onto these behavioural paradigms. The goal of this review is to give a comprehensive overview on how ASD symptoms can be studied in animal models and to give guidance for which ...
Adult-onset T2DM is a complex multifactorial metabolic disorder influenced by genetic, lifestyle and environmental risk factors. Impaired glucose homeostasis in T2DM is primarily characterized by insulin resistance and β-cell dysfunction culminating in the morbidity (nephropathy, neuropathy, retinopathy and...
/ Parkinson's Disease in Women and Men 505 DISEASE PREDICTORS AND RISK FACTORS The etiology of PD is not well understood. Despite the presence of familial cases, PD is substantially an idiopathic, multi-factorial disease caused by the interplay between genetic and environ...
Objective Osteoarthritis (OA) of the knee causes significant morbidity and current medical treatment is limited to symptom relief, while therapies able to ... AD Sawitzke,H Shi,MF Finco,... - 《Arthritis & Rheumatology》 被引量: 462发表: 2010年 ...
It is the only known transplacental carcinogen, and also causes birth defects and genetic changes. It was very widely prescribed for decades to prevent miscarriage so it is very possible his mother was given it. There has not been that much research on its effects on the brain, but it ...