Increasing evidence suggests that inflammatory and immune components in brain are important in Alzheimer’s disease (AD) and anti-inflammatory and immunotherapeutic approaches may be amenable to AD treatment. It is known that complement activation occurs
10]. It is known that urate crystals promote cleavage of C5 on their surface, catalyzing the generation of C5a and C5b-9 involved in gouty inflammation [8]. There is also extensive knowledge of how the crystals activate phagocytes, the role of inflammation signaling and transcription factors,...
get_vals($H,$d=0){global$g;$J=array();$I=$g->query($H);if(is_object($I)){while($K=$I->fetch_row())$J[]=$K[$d];}return$J;}function get_key_vals($H,$h=null,$Xh=0,$hh=true){global$g;if(!is_object($h))$h=$g;$J=array();$h->timeout=$Xh;$I=$h->que...
https://doi.org/10.1037/gpr0000156 Sheldon, K.M., Ryan, R.M., Rawsthorne, L., and Ilardi, B. (1997). Trait self and true self: Cross-role variation in the Big-Five personality traits and its relations with psychological authenticity and subjective well-being. Journal of Personality ...
Cancer is one of the leading causes of mortality and morbidity worldwide. According to 2022 statistics from the World Health Organization (WHO), close to 10 million deaths have been reported in 2020 and it is estimated that the number of cancer cases world-wide could increase to 21.6 million...
In this review, we discuss what is known about the alphavirus exit pathway during a cellular infection. We describe the viral protein interactions that are critical for virus assembly/budding and the host factors that are involved, and we highlight the recent discovery of cell-to-cell ...
Since duramycin binds to PE and the Fc region (fused) IgG antibodies, it interacts with phagocytic cells to enhance phagocytosis. Duramycin is cleared from the site effectively soon after inducing apoptosis in cancer cells, via phagocytosis, which would explain its lower cytotoxicity to surrounding ...