Today, PD is exclusively treated symptomatically, mainly by dopaminergic stimulation, while efforts to modify disease progression could not yet be translated to the clinics. New formulations of approved drugs and treatment options of motor fluctuations in advanced stages accompanied by telehealth ...
Although different black-blood mechanisms can be easily described, their exact performance in terms of SNR, tissue/lumen contrast-to-noise ratio (CNR), and effective resolution are highly dependent on the exact sequence parameters, including both the preparation module and the specific acquisition sche...
A neuroradiologist is a medical doctor who has special training in imaging procedures (diagnostic neuroradiol- ogy) and therapeutic procedures (interventional neu- roradiology) in the brain and spine, as well as the asso- ciated blood vessels and skeletal elements. During their training, neuro...
concept, which is used in several approaches, e.g., PERCIST [5], the visual Deauville criteria [17] or a quantitative extension of the Deauville scale referred to as qPET, has been proposed for the assessment of tumour response to therapy by 18F-FDG PET/CT in paediatric HL patients [18...
Selected issues related to the quantitative analysis of SPECT/CT images were addressed in the present study: (1) What tests can be done to assess the performance of a SPECT/CT gamma camera used for quantitative imaging? (2) Is the level of accuracy of activity measurement obtained by manufact...
Here we used PET and FDG to compare the brain metabolic responses (a marker of brain function) to methylphenidate (a stimulant drug that cocaine abusers report to be similar to cocaine when administered intravenously), between cocaine addicted subjects (n=21) and controls (n=15). In paral- ...
and Europe Methods: We have analyzed a prospectively enrolled cohort of forty-eight patients with HL who were diagnosed in two large university medical centers from 5/2015 to 2/2018. All pts have undergone pretreatment FDG-PET/CT with quantitative analysis of TMTV, Total Lesion Glycolysis (TLG)...
Although it is well known that the nature of a suicidal act (suicide attempt or completed suicide) may be influenced by gender, age, availability of a lethal mean and specific suicidal dimensions, such as suicidal intent and medical lethality, these behaviors seem to have more in common and ...
A recognition and acceptance that a public and population health approach to the management of problem drug users is sound public health policy also then requires a long term commitment in terms of staffing and resources where service delivery mirrors that of chronic condition management. Background ...
In terms of therapy, it is important to know which trajectory a particular carcinoma will follow because of tangible opportunities for drugs to reroute cellular fates towards the first or at least second outcome. These mathematical models have a distinct advantage over clinical observations and cell ...