Typically, when hydrochlorothiazide (HCTZ) is added to an ACE inhibitor or an ARB, there is less risk for hyperkalemia. That’s because HCTZ can decrease potassium levels. Potassium-sparing diuretics, such as: Aldactone (spironolactone) Midamor (amiloride) Inspra (eplerenone) Triamterene Non-...
If you have a kidney ailment, you should not utilize Aldactone, an abnormal amount of potassium in your blood, Addison’s malady (an adrenal organ disorder), if you cannot urinate, or take Eplerenone. Aldactone brought on specific sorts of diseases or tumors in creature studies. You are not...
RALES and EMPHASIS-HF are the two pivotal trials that demonstrated reduced morbidity and mortality with spironolactone or eplerenone, respectively.17, 18 Heightened interest in combining MRAs with potassium-combining resins which bind potassium in the colon to avoid hyperkalaemia (such as sodium ...
A second-generation MRA is eplerenone, which was approved by the FDA in 2003. Compared with spironolactone, eplerenone is more selective, and endocrine side effects occur rarely [79]. The initial dose of eplerenone is 50 mg daily. Eplerenone has a shorter half-life and must be administrated ...