The glomerular filtration rate (GFR) is a measure of how well your kidneys are removing waste from your blood, which can be determined using an estimated GFR (eGFR) test. The test gets its name from glomeruli -- the parts of your kidney that filter out waste. (Photo credit: Image Source...
Cystatin-C-based eGFR: what is it telling us? 来自 掌桥科研 喜欢 0 阅读量: 64 作者:KL Jablonski,M Chonchol 摘要: Cystatin C was introduced as a potential alternative or supplement to the estimation of glomerular filtration rate (GFR) using creatinine. Although cystatin C is well supported ...
Cystatin C was introduced as a potential alternative or supplement to the estimation of glomerular filtration rate (GFR) using creatinine. Although cystatin C is well supported as a better predictor of outcomes than creatinine, its reflection of actual renal function compared with creatinine is widely...
EGFR+ is epidermal growth factor receptor mutation-positive; NSCLC is non-small cell lung cancer. IMPORTANT SAFETY INFORMATION TAGRISSO is an FDA-approved oral targeted therapy used when your NSCLC with certain abnormal EGFR gene(s)* has spread to nearby tissues (locally advanced), that is unable...
Supporting this perspective is work showing that IGF contributes to retinal neovascularization following diabetic retinopathy[168]. Epidermal Growth Factor (EGF) binds to EGFR to induce cellular proliferation, differentiation and survival[169]. The binding of EGF to EGFR has been shown to have a ...
Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine EGFR/Stat3/Sox-2 signaling pathway. Stem Cells 31, 248–258 (2013). Article CAS PubMed Google Scholar Marotta, L. L. et al. The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24...
Whe we choose what to eat,we had better think whether the food will give us the nutrients we need. Some nutrients help build our bodies and make them stronger. We eat fish,meat and beans because the nutrient in them is good for our muscles. We choose eggs,mil...
Lapatinib with ECF/X in the first-line treatment of metastatic gastric cancer according to HER2neu and EGFR status: a randomized placebo-controlled phase II study (EORTC 40071) Cancer Chemother Pharmacol, 82 (2018), pp. 733-739, 10.1007/s00280-018-3667-8 View in ScopusGoogle Scholar [46] ...
A recent phase II clinical trial using anti-NKG2a and anti-EGFR to treat head-and-neck cancer patients showed an improved overall response rate in the majority of patients treated, further highlighting the potential of HLA-E and NKG2a as cancer immunotherapy target combination.126 However, it ...
While the research community has accepted the value of rodent models as informative research platforms, there is less awareness of the utility of other small vertebrate and invertebrate animal models. Neuroscience is increasingly turning to smaller, non-