The purpose of DNA polymerase is to synthesize a DNA molecule using a DNA template. DNA polymerase adds nucleotides in a 5' to 3' direction on a DNA... Learn more about this topic: DNA Replication | Definition, Models & Experiments ...
DNA polymeraseReplication of the DNA occurs for an organism to provide a new DNA strand identical from the parent strand. The DNA contains the genetic information for each organism. DNA could undergo transcription to provide RNA then translation will occur to provide the proteins needed by the ...
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The aim of our laboratory is to determine the mechanisms of resistance to radiotherapy and chemotherapy in cancer cells. We recently discovered that when the expression of a gene called DNA Polymerase theta (POLQ) is reduced using siRNA, cancer cells become more sensitive to radiotherapy 1. The ...
Polymerase is an enzyme found in cells that is used to create DNA and RNA molecules. There are several different types of DNA...
In other words, the cells could not recover from the collision between DNA polymerase and the transcription bubble. As it turns out, scientists have found very little evidence that this type of encounter occurs in nature, which is probably the result of the deleterious, and likely lethal, ...
Because all of the assays are amplified in the same tube, they compete for the same reagents (dNTPs, Mg2+, and polymerase). The more targets that are assayed in a multiplex reaction, the more likely it is that there will be competition for reagents and inhibiti...
During PCR and cycle sequencing, the DNA is first denatured (the double-stranded DNA template becomes single-stranded DNA). A subsequent annealing step allows for hybridization of the oligonucleotide primer close to the sequence of interest. In the extension...
Reverse transcriptase, also called RNA-directed DNA polymerase, an enzyme encoded from the genetic material of retroviruses that catalyzes the transcription of retrovirus RNA (ribonucleic acid) into DNA (deoxyribonucleic acid). This catalyzed transcription is the reverse process of normal cellular transcrip...
Social sciences DNA What role does the DNA polymerase I play in the leading strand vs. the lagging strand?Question:What role does the DNA polymerase I play in the leading strand vs. the lagging strand?DNA Replication:DNA replication is the process by which a cell's DNA...