Benign prostatic hyperplasia (BPH) is a condition caused by the proliferation of glandular epithelial cells in the prostate and occurs more commonly in intact dogs over five years old. It causes painful or strained urination with evidence of blood in the semen, urine or faeces. The authors carri...
Celiac disease (CD) is a chronic autoimmune disorder [ 1 ]. It is an enteropathy of the proximal small intestine characterized by villous atrophy, various degrees of crypt cell hyperplasia and increased numbers of intraepithelial lymphocytes [ 2 – 4 ]. An altered immune response to dietary ...
Eosinophils within the muscularis mucosae are also abnormal and can be a helpful finding when the diagnosis is suspected. Patients with malabsorptive symptoms may have small bowel biopsies that show eosinophilia as well as partial, or complete villous shortening with crypt hyperplasia and variable ...
Celiac disease is a lifelong autoimmune condition caused by intolerance to the dietary gluten in genetically predisposed individuals resulting in villous atrophy, inflammation, and crypt cell hyperplasia in the proximal small intestine. The detection of gluten-reactive CD4+ T cells producing interferon-γ...
A cobblestone appearance is an uncommon finding, where polygonal cells bulge out from the mucosal surface to a varying degree, and it is usually seen in the posterior pharyngeal wall or laterally behind the tonsillar pillars; it supposedly reflects lymphoid nodular hyperplasia of the immune system ...
Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract. J Neurosci. 1996;16:2352-2364. [PubMed] [Cited in This Article: 1] 198. Li J, Ma W, Wang S. Slower gastric emptying in high-fat diet induced obese rats is associated with attenuated ...
the progression of chronic airway inflammatory diseases. Cystic fibrosis (CF) is an autosomal recessive genetic disease that affects multiple organs, such as the respiratory tract, pancreas, intestine, and liver, and is characterized mainly by mucinous gland hyperplasia and viscous secretions. The ...
GERD, itself characterized by squamous hyperplasia, elevated presence of intraepithelial inflammatory infiltrate, epithelial cell necrosis and lack of surface maturation, is a precursor to BE. The metaplastic columnar epithelium of BE appears to be more resistant to reflux-induced injury than the native...
Distinctive duodenal histology features are the profound depletion of plasma cells and follicular lymphoid hyperplasia. It does not respond to intravenous immunoglobulin, nor to a GFD, but steroids are highly effective [113]. Lastly, tropical sprue should be suspected in residents or travelers to ...
Analysis revealed serositis, hepatic and renal fibrosis, hepatomegaly, hepatic necrosis, nodular hyperplasia, acute necrosis in adipose tissue, and formation of adhesions of the liver to the diaphragm or to the right kidney. The authors suggest an affinity of SMF for specific receptors in proximal...