Both the ACCORD Lipid and the FIELD studies subsequently showed that increases in serum creatinine associated with fenofibrate were reversible, with levels returning to those observed in the placebo group about 6–8 weeks after cessation of treatment, and did not appear to detrimentally influence ...
While it is unlikely that most medical practitioners will ever encounter nerve agent poisoning, it is critical to be aware of the presenting symptoms and how best to treat patients exposed to these deadly agents. History has shown that rapid medical treatment can easily mean the difference between...
Metabolic state has also been assessed by measuring urine triiodothyronine in macaques [114], by determining C-peptide and ketone bodies in orangutans [124], and by assessing the nitrogen:creatinine ratio in wild moose [125,126]. In arboreal mammals, urine can often be collected from the ...
Although many PopPK models for aminoglycosides exist in the literature, important variability remains. Despite multiple covariates being tested across all studies, the significant covariates would still be creatinine clearance and bodyweight for aminoglycoside clearance and volume of distribution, respectively...
Of most concern is the hyperkalemia which needs to be immediately addressed. In addition to myoglobin breakdown products, creatinine phosphokinase (CPK) may be elevated. The level of serum CPK has been correlated to the risk of acute kidney injury. In the setting of intensive care patients, a ...
Despite the intense research to discover other biomarkers, in addition to proteinuria and creatinine, no other biomarker proved to be useful for the follow-up of Anderson–Fabry nephropathy [10]. However, proteinuria/albuminuria is not an early marker of renal damage, since in the early stages ...