Leukemia is cancer of the blood or bone marrow. Bone marrow produces blood cells, so individuals who have leukemia have an abnormal production of blood cells. Usually the abnormality is with the leukocytes, or white blood cells, and is the result of damage to the DNA of...
This article discusses monitoring and treatment of patients with CML after failure of or suboptimal response to imatinib therapy. We reviewed articles listed on PubMed from January 1, 2002, to July 31, 2008, and abstracts from the 2007 Annual Meeting of the American Society of Hematology. ...
摘要: PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.关键词: Humans Catheterization, Central Venous Catheterization, Peripheral...
Article CAS PubMed Google Scholar Jiang, F. et al. Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer. Mol. Cancer Res. 7, 330–338 (2009). Article CAS PubMed PubMed Central Google Scholar Rasheed, Z. A. et al. Prognostic significance of tumorigenic cells...
Haz-Map is now published on ExPub. See www.expub.com. Some new features of this version are the inclusion of carcinogen classifications from NTP and ACGIH, links to ERG 2008 Guides, and hyperlinked PubMed references. September 24, 2011 I made a presentation on "Exposure Assessment" at the...
and prospects. The limitations of standardization in current scientific production are analyzed, along with possible solutions proposed by some of the referenced papers. As the continuous evolution of medical imaging is ongoing, radiologists must be aware of new perspectives to play a central role in...
Article PubMed CAS Google Scholar Margolese RG, Fisher B, Hortobagyi GN: Neoplasms of the Breast. Holland-Frei Cancer Medicine. Edited by: Bast RCJr, Kufe DW, Pollock RE. 2000, Hamilton (ON): BC Decker, 5 Google Scholar Lichtenstein P, Holm NV, Verkasalo PK, Iliadou A, Kaprio ...
Unfortunately, the exclusive dependence of CML cells on signaling through the Bcr-Abl pathway is the exception rather than the rule for malignancies in general, and it quickly became apparent that cotargeting of multiple cooperative survival pathways must be employed to overcome the marked redundancy ...
Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function. Cancer Res 2001; 61: 3443–3449. CAS PubMed Google Scholar Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N et al. Bcl-2 antiapoptotic proteins inhibit ...
suggested that expression of FBXW7 has implications in cancer drug resistance and that ablation of FBXW7 in combination with anti-cancer drugs might be a promising therapeutic strategy for chronic myeloid leukemia (CML) patients. For instance, CML, the leukemia-initiating cells (LICs) remained ...