aN-oxide was comparable to that observed in adults, and the Cmax and AUC0-12[translate] ait's so sale 它如此是销售[translate] aand pray to god he will do for us easy. our parents may live like prince and princess of kingdom 并且祈祷对神他意志C为习惯容易。 我们的父母也许居住象王子和...
aAdministration IV established the basic PK parameters, clearance, half-life and distribution volumes and IM dosing (the likely route of administration in sheep in clinical use) established the PK variables Cmax, AUC and bioavailability (Toutain and Bousquet-Melou, 2004a,b). 管理IV建立了基本的PK...
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MAIN OUTCOME MEASURES: Colchicine is metabolized via cytochrome P450 3A4 (CYP3A4); therefore, coadministration with agents that inhibit this isoenzyme can produce elevated colchicine plasma concentrations, resulting in severe and sometimes fatal adverse events. Knowledge of the potential for drug-drug ...
elimination half-life of about 4 to 5 times and an increase in the AUC value of 5 to 7 times. However, the Cmax and volume of distribution are not significantly different from those of normal metabolizers. In poor metabolizers, the proportion of unchanged drug excreted in urine is greater...
within 90-180 minutes. The half-life of gemcitabine after intraperitoneal administration is 101.6 minutes, and the ratio of intraperitoneal AUC to plasma AUC is 12.5 ± 3.2. 70% is absorbed into the plasma within 3 hours after administration, and 90% is absorbed into the plasma within 6 ...
Antibiotic pharmacodynamics is an evolving science that focuses on the relationship between drug concentration and pharmacologic effect, which is an antibiotic-induced bacterial death that also can manifest as an adverse drug reaction. The pharmacologic action of antibiotics usually can be described as ...
That's okay ... everyone's journey will be filled with hopes, dreams, challenges, setbacks and goodbyes. We must strive to make the best of it ... no matter what. We must constantly strive to understa...
and the organ distribution test showed that active substances could be detected in the heart, which once again confirmed that the target organ of the drug was the heart. Although there is no obvious accumulation of drugs in the body, Cmax and AUC in the high-dose group tend to increase wit...
aWhen Onpito (TJ-8117, Kampo medicine) containing licorice and rhubarb was administered orally to human subjects, we observed that the AUC(0—lim) and Cmax of glycyrrhetic acid (GA) in plasma were lower than those treated with other Kampo medicines containing licorice. 正在翻译,请等待...[...