(CHD) to be of clinical value, they need to provide information over and above conventional risk factors (CRFs) currently used in risk algorithms, such as the Framingham Risk Score, which incorporates CRFs such as age, gender, blood lipid concentrations, blood pressure, body mass index, ...
Coronary heart disease (CHD) is a group of different types of heart disease. Common heart disease symptoms include chest pain, shortness of breath, palpitations, light-headedness, and dizziness. Heart disease has many causes, including genetics, atherosc
If a person has only one copy of a variant gene, they are considered a carrier. A carrier can pass along the gene for the condition to their children but will not have symptoms themselves. As a result, unless Usher syndrome is known to be present in a person's family, they may not ...
Secreted phospholipases of type A2 (sPLA2s) are proteins of 14–16 kDa present in mammals in different forms and at different body sites. They are involved in lipid transformation processes, and consequently in various immune, inflammatory, and metabolic processes. sPLA2s are also major componen...
As in almost any epidemiological issue, the case is complex, and there is confusion between ‘the lipid hypothesis’ of the cause of high-cholesterol, and the explanation of coronary heart disease with a diet high in animal fats. However, there is little doubt that the focus on the role ...
However, LDL is a com- by activated platelets may also induce the oxidativeSome interesting questions could be raised by our modifica- plex particle consisting of a lipid core surrounded by apolipoprotein tion of Apo B-100 in the absence of lipid peroxidation of LDL.Oxidized LDL: biomarker ...
LDL-C relating to CVD risk is based on a weak chain of causality: the Dietary Fat hypothesis —> working via the Lipid Hypothesis, which then supposedly accounts for CVD events: nope, sorry, this has been constantly shown to break down right from the Dietary Fat hypothesis. ...
Five years on, the key question must be: Are we closer to defining the optimal therapeutic strategy for reducing lipid-related residual CV risk? New insights: what is the relevance of HDL versus TRLs to residual risk? Emerging evidence provides new insight into the relative importance of TRLs...
“that there is no significant evidence for concluding that dietary saturated fat is associated with an increased risk of CHD or CVD,”[vii] or even more recently, that the “current evidence does not clearly support cardiovascular guidelines that encourage high consumption of polyunsaturated fatty ...
Prior to getting discharged I was hooked up to a 30-day heart monitor test. This is a system where three adhesive patches are attached to my chest and those wires go down to a pager-sized device on my belt. That device, then sends a wireless signal (Bluetooth?) to a modified mobile ...