Cerebral amyloid angiopathy (CAA) is an age-related small vessel disease pathologically characterized by the progressive accumulation of amyloid-beta (A尾) peptide in cerebrovascular walls, affecting both cortical and leptomeningeal vessels. Amyloid deposition results in fragile vessels, which may lead to...
Cerebral amyloid angiopathy (CAA) has similar AD pathologies associated with Aβ accumulation and inflammation in the brain. Zabel et al.[95] has examined human post-mortem brains with concomitant CAA and AD with purely parenchymal pathology and for differential expression of microglia-associated Aβ...
BACKGROUND: Periventricular white matter hyperintensities (PVWMHs) in cerebral amyloid angiopathy (CAA) have been reported posterior predominant using semi... L Deasy,S Laurent-Chabalier,ERD Wacongne - 《Stroke A Journal of Cerebral Circulation》 被引量: 0发表: 2024年 ATTR Cardiac Amyloidosis: Cla...
Pathogenic effects of cerebral amyloid angiopathy mutations in the amyloid beta-protein precursor. Moreover, the presence of both CAA substitutions in the same Aβ peptide further enhances the fibrillogenic and pathogenic properties of Aβ. We also ... WEV Nostrand,JP Melchor,G Romanov,... -...
These results support the notion that EPVS in the BG may be a marker ofCSVD.[22],[28] The results of a prospective cohort study showed that WM-EPVS was associated with cerebral amyloid angiopathy (CAA) and superficial siderosis.[29] Conversely, a prospective, multicenter, hospital-based stu...
Background Intracerebral haemorrhage(ICH) accounts for approximately 20% of all strokes and is a leading cause of disability and mortality. The distribution of the ICH(Lobar v Deep) may be explained by the two major aetiologies of ICH, Cerebral Amyloid Angiopathy (CAA) versus hypertensive...