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interferon, transforming growth factor (TGF) and tumor necrosis factor (TNF), which are used in cancer, apoptosis, endocrinology, immunology, neuroscience, protease and stem cell research. These cytokines have been rigorously verified to meet the demand of R&D personnel for high quality, ...
Biliary atresia (BA) is a rare disease of unknown etiology and unpredictable outcome, even when there has been timely diagnosis and exemplary surgery. It has been the commonest indication for liver transplantation during childhood for the past 20 ye
enucleate - remove the nucleus from (a cell) decorticate - remove the cortex of (an organ) bail - remove (water) from a vessel with a container undress, disinvest, divest, strip - remove (someone's or one's own) clothes; "The nurse quickly undressed the accident victim"; "She divest...
In-Cell ELISA Benefits Several factors should be considered when deciding what assay to use. Western Blot is a commonly used assay for detecting and measuring proteins in cells. However, In-Cell ELISA has several advantages over Western Blot: it is more sensitive, specific, and quantitative....
Veliparib dihydrochloride, also known as ABT-888 dihydrochloride, is a potent inhibitor of PARP1 and PARP2 with Ki values of 5.2 nM and 2.9 nM, respectively, in cell-free assays. It is ineffective against SIRT2. So, what exactly is its biological activity and how can it be tested? Let'...
Request A Free FBS SampleView All FBS Key Quality Tests for FBS Consistency Plating Efficiency Plating efficiency is used to assess the ability of serum to facilitate cell adherence to solid surfaces for growth. One common assay for this uses A549 human lung carcinoma cells, plated at low densit...
The mechanism of single- or double-stranded passage that follows the cleavage of a first DNA molecule is tightly regulated to prevent the accumulation of DNA breaks that can lead to cell death. Structural investigations of the catalytic cycle of the type IA and type IIA enzymes have provided ...
Since then, it has become increasingly apparent that the tumor environment (TEM), whose major components are non-neoplastic cell types, is also of utmost importance for our understanding of tumor growth, maintenance and resistance. In this review, we present the current knowledge concerning all ...