9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook AcronymDefinition SCD40LSoluble CD40 Ligand Copyright 1988-2018AcronymFinder.com, All rights reserved. Suggest new definition Want to thank TFD for its existence?Tell a friend about us, add a link to this page...
Human dendritic cells discriminate between viable and killed Toxoplasma gondii tachyzoites: dendritic cell activation after infection with viable parasites results in CD28 and CD40 ligand signaling that controls IL-12-dependent and -independent T cell production of IFN-gamma. J. Immunol. 165, 1498–...
CD40 LigandAntigens, CD28The development of autoimmune diabetes in the nonobese diabetic (NOD) mouse results from a breakdown in tolerance to pancreatic islet antigens. CD28-B7 and CD4O ligand-CD4O (CD4OL-CD4O) costimulatory path- ways affect the development of disease and are promising ...
PD-L1: Programmed death ligand 1 PFS: Progression-free survival PK: Pharmacokinetics RCC: Renal cell carcinoma SD: Stable disease TDO: Tryptophan 2,3 dioxygenase TME: Tumor microenvironment TGC: Tumor growth control Treg: Regulatory T cell TRP: Tryptophan ...
Programmed death ligand 1 PFS: Progression-free survival PK: Pharmacokinetics RCC: Renal cell carcinoma SD: Stable disease TDO: Tryptophan 2,3 dioxygenase TME: Tumor microenvironment TGC: Tumor growth control Treg: Regulatory T cell TRP: Tryptophan ...
Redesigning an FKBP–ligand interface to generate chemical dimerizers with novel specificity. Proc Natl Acad Sci USA 1998;95(18):10437–10442. doi:10.1073/pnas.95.18.10437. (Open in a new window)PubMed (Open in a new window)Web of Science ®(Open in a new window)Google Scholar ...
rPSGL-Ig (Thios Pharmaceuticals, Emeryville, CA) is a novel fusion protein resulting in the combination of the binding portion of the high-affinity P-selectin glycoprotein ligand-1 (PSGL-1, CD62) and the Fc domain of human IgG1 (39). P-selectin along with E-selectin and l-selectin, ...
the CD40 ligand transcripts in that patient's T cells had a deletion of 10 base pairs (bp) in the extracellular domain of the CD40 ligand (nu- cleotides 447 to 456). The intragenic CD40 ligand microsatellite probe revealed a polymorphism... C Thomas,GDS Basile,Franoise Le Deist,... - ...
Tat is also capable of inducing apoptosis in Bim-/-cells [89]. Another pathway by which Tat has been shown to induce the apoptosis of bystander CD4+T cells is by upregulating Fas ligand (CD178) expression in both infected and uninfected bystander cells [14,15,93]. HIV-1-infected individ...
this mechanism causes the fibrous plaque to degrade. Proteinases mediated by inflammatory signaling mediate decreased synthesis, while IFN- mediates increased breakdown. The expression of tissue factor, a significant cause of thrombus development, is improved by CD40 ligation, increasing the thrombogenicity...