Both the absolute concentrations and the ratio are utilized to diagnose plasma cell dyscrasias, provide prognostic information, monitor response to therapy, and assess relapse.10 When the light chain isoform of the paraprotein is known, the difference between the affected and unaffected sFLC (also ...
Bone disease is the most frequent feature of multiple myeloma (MM) and represents a marker of end-organ damage, used to establish the diagnosis and to dictate the immediate need of therapy. For this reason, imaging plays a significant role in the managem
Plasma cell proliferative index is an independent predictor of progression in smoldering multiple myeloma. Blood Adv. 2018, 2, 3149–3154. [Google Scholar] [CrossRef] [PubMed] [Green Version] Fernández de Larrea, C.; Isola, I.; Pereira, A.; Cibeira, M.T.; Magnano, L.; Tovar, N....