There is no available vaccine for Chagas disease and the treatment mainly relies on the nitroheterocyclic compounds Benznidazole (BZN) and Nifurtimox (NFX), which have been in use for over half a century, face safety issues, and variable efficacy according to the phase of the disease [3,4]....
Regarding treatment, there are two anti-parasitic medications (called benznidazole and nifurtimox) that can be used for both those who test positive and are asymptomatic and those who have symptoms of chronic disease. The drugs can have significant side effects, andpatientson these medications need ...