Assay for transposase-accessible chromatin sequencing (ATAC-seq) and H3K27ac ChIP-seq showed that GATA2AS is essential to maintain the chromatin regulatory landscape during erythroid differentiation. Knockdown of GATA2AS in human primary ... G Liu,J Kim,N Nguyen,... - 《Blood》 被引量: 0...
Single-cell epigenomics, such as single-nucleus ATAC-seq (to characterize chromatin accessibility) or DNA methylation-sequencing, has also been used to generate cell type atlases for different brain regions that are consistent with transcriptomic cell atlases and further reveal cell type-specific gene ...
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Nevertheless, the catalytic activity of GCN5 is stimulated collectively by all subunits of the ADA2a-containing HAT module, and is further increased when the HAT module is incorporated in the ATAC holo-complex [116]. These observations suggest that the interactions of the HAT with the other ...
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