What is an open reading frame (ORF)?The nucleotides of a gene that make up the codons specifying amino acids.
mRNA degradation, which has traditionally been thought to result from stop codons that terminate translation more 5′ than is usual on an mRNA. Short ORFs (sORFs). Open reading frames of fewer than 100 codons on mRNAs that are not known to encode a canonical (long) protein. sORFs are a ...
Pestiviruses are single-stranded (ss) RNA viruses with an envelope containing three viral glycoproteins, i.e., Erns, E1, and E2. The genome with positive polarity encodes for a single large open reading frame (ORF). By virtue of a large variety of possible mutations, BVDV exists as a cy...
The mechanism underlying regulation of UCP2 translation by glutamine has been deciphered [4]: the translation of UCP2 from the UCP2 mRNA is normally inhibited because of the existence of an upstream open reading frame (uORF) in the long 5′ untranslated region of the UCP2 mRNA [3], [40...
Unit 2 what is a gene基因是什么 Unit2Whatisagene?“Gene”的妙译★Gene[dʒi:n]:基因。★译者：摩尔根的弟子谈家桢院士。★妙处：兼顾语音和词义。Definition1860s–1900s:Geneasadiscreteunitofheredity Theconceptofthe―gene‖hasevolvedandbecomemorecomplexsinceitwasfirstproposed.Therearevariousdefinitionsof...
The reading frame of an mRNA is determined by: a. The initiation codon (usually the first AUG) b. The first nucleotide of the mRNA c. the stop codon d. the transcription start site What amino acid does the codon AGG code for?
It is also called thehepatitis B core antigen. It also acts as an active indicator of viral replication. This antigen can be found on the surface of the nucleocapsid core. Both HBcAg and HBeAg are made from the same open reading frame. However, it is considered particulate or non-secretory...
byopen reading framegenes (ORF-1aandORF-1b)[14]. This helps to hijack the host’s cellular machinery and take control of the host ribosomes, for their own replication and translation processes [15]. Besides, the viral proteins ORF-3a, ORF-3b, ORF-6, and ORF-7a have the ability to ...
The SF1 helicase protein of viruses classified in the order Nidovirales is encoded in replicase open reading frame 1b (ORF1b), which is translated to give rise to a large polyprotein following a ribosomal frameshift from the upstream ORF1a. Proteolytic processing of the replicase polyprotein ...
The reading frame of an mRNA is determined by: a. The initiation codon (usually the first AUG) b. The first nucleotide of the mRNA c. the stop codon d. the transcription start site What must tRNAs bind to during translation? a. ribosome b. nucleus c. phosphate d. exon e. codon ...