We must consider whether a patient with an EF of 44% is different from one with an EF of 46%, if both are asymptomatic? Further, trials often mandate a pre-trial ECG to have a QTc < 450 ms. However, there is poor concordance between the different criteria used to measure corrected ...
OGE/RPIE OGEA OGEAD OGEB OGEC OGED OGEFI OGEH OGEHR OGEI ÖGEKM OGEL OGEM OGES OGET OGETA OGEU OGEV OGF ÖGF OGFA OGFAA OGFB OGFC OGFICE OGFJ OGFP OGFR OGFT OGFUDA OGFX OGG OGGG ÖGGG OGGH OGGI OGGMB OGGO
The HH ligand is bound by a large multipass transmembrane protein called Patched (PTC). In the absence of HH, PTC inhibits the signalling activity of the seven-pass transmembrane protein Smoothened (SMO); however, once PTC has bound HH, this inhibition is relieved and SMO can trigger an ...