Only one NDRI is approved by the FDA to treat depression —bupropion(Wellbutrin®). Along with the Wellbutrin moniker, bupropion is also sold under the brand names Wellbutrin SR® and Wellbutrin XL® to treat depression and seasonal affective disorder. When sold under the brand name Zyban...
Bupropion (Wellbutrin) Fluoxetine (Prozac), Sertraline (Zoloft) 12 Mechanism of Action Inhibits reuptake of norepinephrine and dopamine Inhibits reuptake of serotonin 14 Compare with Definitions NDRI It may cause fewer sexual side effects compared to SSRIs. Patients switching to an NDRI often report ...
Wellbutrin, also known as bupropion, is one of the more commonly prescribed antidepressants. The drug is a norepinephrine-dopamine reuptake inhibitor, or NDRI. Basically, the medication alters a person’s mood by increasing dopamine levels in the brain. Dopamine, like serotonin, is a chemical that...