These patients are on high dose prednisone for the chronic GVHD which they have but the steroid is not effective, or there is an attempt to reduce the dosage or eliminate prednisone completely. This phase 1 clinical trial is hoping to see is the effect can reduce/eliminate the prednisone ...
Parkinson’s disease is one of the most common disorders of the midbrain. This progressive illness develops when dopamine-producing nerve cells in the pars compacta die off in large numbers. These nerve cells are important in regulating motor function and emotion, and cell death leads to symptoms...