Hemostasis or haemostasis is a process to prevent and stop bleeding, meaning to keep blood within a damaged blood vessel. It is the first stage of wound healing.
VWD-type 1 is characterized by a partial quantitative deficiency in VWF. VWD-type 2 refers to qualitative VWF defects with several subtypes (2A, 2B, 2N, and 2M) according to the patients' functional defect. Finally, VWD-type 3, also called severe VWD, is manifested by a virtually complete...
In this issue of Blood, Sorvillo and colleagues demonstrate that a macrophage mannose receptor (MR) on antigen-presenting cells facilitates uptake of ADAMTS13 antigen. 1 The findings provide the first hint on how ADAMTS13 antigen may be endocytosed, processed, and presented to immune T cells. ...
Long COVID-19 is a recognized entity that affects millions of people worldwide. Its broad clinical symptoms include thrombotic events, brain fog, myocarditis, shortness of breath, fatigue, muscle pains, and others. Due to the binding of the virus with ACE-2 receptors, expressed in many organs...
Deficiency of ADAMTS-13 results in failure of cleavage of ULvWF multimers. Thrombotic Microangiopathies: Role of ADAMTS-13 ADAMTS-13 digests ULVWF multimers as they are synthesized and secreted by endothelial cells. ABBREVATIONS: ADAMTS = a disintegrin-like and metalloprotease domain with thrombosp...
There are many types of anemia. Iron-deficiency anemia is a common one that happens when people don't have enough iron. Your body needs iron to make healthy red blood cells. This type of anemia may happen if you don't get enough iron in the food you eat or your body doesn't take ...
Want to thank TFD for its existence?Tell a friend about us, add a link to this page, or visitthe webmaster's page for free fun content. Link to this page: Facebook Twitter Acronyms browser? â–² ULKY ULL ULLA ULLC ULLCA ...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a potentially life-threatening disease, defined as Coronavirus Disease 19 (COVID-19). This pathological condition is generally characterized by the presence of several signs and symptoms. The most common ones include cough, sore thr...