reported that human FcεRI β-chaingene expression was down-regulated by a transcription factor,MZF-1, through an element in the fourth intron. In the present study, we found that this transcriptional repression by MZF- startThe高亲合力IgE感受器官FcεRI在triggeringallergic反应扮演一个关键角色...
Transcription factor binding kinetics and transcriptional bursting: What do we really know?In eukaryotes, transcription is a discontinuous process with mRNA being generated in bursts, after the binding of transcription factors (TFs) to regulatory elements on the genome. Live-cell single-molecule ...
Blimp-1 over Budapest: Blimp-1 is a transcription factor that affects the expression of hundreds of genes in lymphocytes. Recent work confirmed its role in the maturation of B cells into immunoglobulin-secreting plasmablasts, as well as in the control of T cell homeostasis and tolerance. What ...
Their transport capacity is conferred by an... CE Offler,JW Patrick - 《New Phytologist》 被引量: 0发表: 2020年 Transcriptional Regulation of Plant Secondary Metabolism Plant secondary metabolites play critical roles in plant-environment interactions.They are synthesized in different organs or tissues...
What is the effect of mutations on the structure of proteins? Some transposons replicate when they move. What effect does this have on the genome? What would be the impact of a mutation that eliminates transcription factor (tf3) on the expression of gene 2 (g2)? A. It would produce more...
atranscriptional intermediary factor transcriptional中介因素[translate] aWe have received your list of shipped items. However we need the 24” x 5-ply and the discharge hoses. When can you ship them 我们接受了运输的项目您的名单。 然而我们需要24” x 5使用和放电水喉。 当能您运输他们[translate]...
The Son Of X-Shooter (SOXS) will be the specialized facility to observe any transient event with a flexible scheduler at the ESO New Technology Telescope (NTT) at La Silla, Chile. SOXS is a single object spectrograph offering simultaneous spectral coverage in UV-VIS (350-850 nm) and NIR ...
being difficult to validate a candidate as pathogenicity factor by RNAi gene silencing techniques [73,74,82]. CRISPR/Cas9 is a powerful experimental tool for gene-editing [83] and is clearly an emerging tool for functional genomics, opening new opportunities for functional analysis in many ...
It was recently revealed that the motifs of a transcriptional factor, Activator protein 1 (AP-1) is essential to CM proliferation, dedifferentiation and protrusion during zebrafish heart regeneration after injury by remodelling CM chromatin accessibility. CM-specific KO of Fos (one of the subunits ...
Combinations of these modifications are thought to constitute the so-called “histone code” which can be read and interpreted by different cellular factors leading to transcriptional activation or repression.2For example, a general characteristic of euchromatin is tri-methylation at lysine residues of ...