therapeutic equivalenceThe problem of generic drugs use in clinical practice and confirmation of their therapeutic equivalence is discussed. The significance of studies on generic drugs bioequivalence, as well as details of international practice and regulations in this area is explained....
According the to FDA, a biosimilar is a biological product that is highly similar to, and has no clinically meaningful differences from an existing FDA-approved reference product. Biological products are a diverse category of products, and include therapeutic proteins (example filgrastim) and monoclona...
Therapeutic drug monitoring to adjust dosing in morbid obesity – a new use for an old methodology The phenomena of hunger and need at one end of the spectrum and obesity and plenty on the other is an anomaly of the 21st century, likely to be due to a co... JH Martin,M Saleem,D Lo...
What is meant by "electron carrier?" Briefly describe one factor that can increase the risk of drug addiction, and one protective factor that can reduce the risk of drug addiction. (a) How does the adverse effect of a drug occur? (b) What are the causes of some drug-drug interactions?
Because both drugs contain amphetamines, they work in a similar way. Studies have shown that Vyvanse is just as effective as Adderall, and side effects are similar. The risk of dependence (this means how likely you are to become dependent or addicted to the drug) appears similar for both Ad...
Contrary to popular thought, people don’t choose to develop obesity; most people don’t wake up one morning and think, “Hey, today is a good day to become overweight to the point where it might damage my health and well-being.” Obesity is a result of a complex back-and-forth inter...
What Is Ketamine? From anesthetic to party drug to antidepressant, ketamine has evolved significantly since the 1960s. How can it treat depression without harmful side effects? Emergency responders may give it to an agitated patient who, for example, they have rescued from asuicideattempt. That’...
Hope and love are popular themes of literature and art in many human societies. The human physiology of love and hope is less well understood. This review presents evidence that the lack of love and/or hope delays growth disturbs development and maturati
Part of the COVID-19 illness is viral lung infection (viral pneumonia). A small number of viral pneumonias can also develop a bacterial infection within the lung. The addition of the bacterial infection on top of the viral infection is called a secondary bacterial infection. ...
A placebo (or dummy pill) is an inactive substance, typically a tablet, capsule or other dose form that does not contain an active drug ingredient and has no pharmacologic action. Research has shown that a placebo treatment can have a positive therapeutic effect in a patient, even though the...