What is somatic mutation? Mutation: A mutation can be described as the change in the nucleotide sequence of a gene, which is responsible for resulting in either the formation of a defective protein or no protein at all. The mutation can also alter the regulation of certain genes leading to ...
What is the EFEMP2 genetic mutation? Explain whether a mutation affects the organism itself or the organism's offspring. What are some ways that mutations can actually be a positive thing? Describe the mutation process. The NSRD mutation is a harmful mutation. Why might someone with this muta...
What is an Hypomorphic allele? Hypomorphic describesa mutation that causes a partial loss of gene function. A hypomorph is a reduction in gene function through reduced (protein, RNA) expression or reduced functional performance, but not a complete loss. The phenotype of a hypomorph is more seve...
The hunt for pathogenic mitochondrial DNA (mtDNA) mutations is often fueled by the seeming novelty of mutations that are either nonsynonymous or affect the protein synthesis machinery in patients. In order to determine the novelty of a detected mutation, the working geneticist nearly always consults...
It has been proposed that somatic mutations make major contributions to aging. The first paper, based on a gene knock-in mouse, supports a contributory role for mutation in mtDNA[ 1 ] in aging, but does not support a damaged-mtDNA-producing-more-damaged-mtDNA hypothesis.[ 1 ] The second ...
NCERT solutions for CBSE and other state boards is a key requirement for students. Doubtnut helps with homework, doubts and solutions to all the questions. It has helped students get under AIR 100 in NEET & IIT JEE. Get PDF and video solutions of IIT-JEE Mains & Advanced previous year pap...
Editors' Picks Related Articles What is a Gene Mutation? What is BRCA Mutation? Discussion Comments WiseGeek, in your inbox Our latest articles, guides, and more, delivered daily. Subscribe Categories Health Technology Finance Culinary Culture ...
SpringerPlus 2012, 1:83 http://www.springerplus.com/content/1/1/83 a SpringerOpen Journal REVIEW Open Access Seventeen years after BRCA1: what is the BRCA mutation status of the breast cancer patients in Africa? – a systematic review Lawal AbdulRazzaq Oluwagbemiga1*, Atoyebi Oluwole1 and...
which refers to the various cells of one’s body that are not involved in reproduction; skin cells for example. If the replication of a cell with a somatic mutation is not stopped, then the population of aberrant cells will expand. However, somatic mutations cannot be passed on to an organ...
An acquired (somatic) mutation does not originate from a parent or blood relative. Rather, a child obtains it later on in his or her life. The mutation starts in a single cell, and is then passed on to new cells formed from the original cell. This mutation is not present in eg...