Tightly bonded cofactors are known as prosthetic groups, and loosely bonded cofactors are typically referred to by the broader term coenzymes. The first cofactor was isolated in 1906, in yeast, but cofactors can be organic or inorganic. The most important function of coenzyme A is to aid in ...
A fad is a prosthetic group that is available in several enzymes. Coenzyme The coenzyme binds to the enzyme only during the catalysis process. For other times, it is separated from the enzyme. NAD+ is an example of a coenzyme. Metal ions...
The Biology of Erections Typically, when a man is sexually aroused, nerve impulses signal an increase in blood flow to the penis. The blood then enters two erection chambers within the penis composed of spongy tissue known as the corpus cavernosum. The smooth muscle fibers within the erection ...
Haemoglobin (Hb) is a type of globular protein present in red blood cells (RBCs), which transports oxygen in our body through blood. It is a tetrameric protein and contains the heme prosthetic group attached to each subunit. It is a respiratory pigment and helps in transporting oxygen as ox...
Periodontitis has been commonly linked to periodontopathogens categorized in Socransky’s microbial complexes; however, there is a lack of knowledge regarding “other microorganisms” or “cryptic microorganisms”, which are rarely thought of as significant oral pathogens and have been neither previously...
The real impact of nanoparticles on male fertility is evaluated after a careful analysis of the available literature. The first part reviews animal models to understand the testicular biodistribution and biopersistence of nanoparticles, while the second part evaluates their in vitro and in vivo biotoxi...
act as charge carriers. An example of a prosthetic group is heme in hemoglobin, myoglobin, and cytochrome. The iron (Fe) found at the center of the heme prosthetic group allows it to bind and release oxygen in the lung and tissues, respectively. Vitamins are also examples of prosthetic ...
Despite the fact that in IBS subjects macroscopically evident pathological lesions at colonoscopy have not been found, molecular biology and in-depth histological investigations have revealed the activation of the immune system. A key piece of evidence is that the exposure of rodent[18-20] or human...
J P BonjourPubMedFleisch H, Caverzasio J, Bonjour JP. Regulation mechanisms of the renal phosphate handling in renal failure--What is the role of PTH? In: Advances in experimental medicine and biology, vol 151. New York: Plenum Press, 1982....
Bacterial infections are the leading cause of death in people with a spinal cord injury (SCI). Bacteriophages (phages) are viruses that solely infect and kill bacteria. The idea of using phages to treat bacterial infections, i.e., phage therapy, is very