What is a pragmatic trial; Difference between a pragmatic trial and a explanatory trial; Why bias is generally not seen in a pragmatic trial; Outcome measures differences between explanatory and pragmatic approaches.关键词: Selection Bias Clinical Trials as Topic ...
KJL Bell,A Mccullough,C Del Mar,P Glasziou 摘要: Effectiveness of interventions in pragmatic trials may not translate directly into population impact, because of limited uptake by clinicians and/or the public. Uptake of an intervention is influenced by a number of factors. We propose a method ...
Effectiveness of interventions in pragmatic trials may not translate directly into population impact, because of limited uptake by clinicians and/or the public. Uptake of an intervention is influenced by a number of factors. We propose a method for calculating population impact of clinical ...
Randomized controlled trials (RCTs) may be categorized as either effectiveness trials or efficacy trials, which may be categorized by the Pragmatic-Explanatory Continuum Indicator Summary (PRECIS) tool. However, no data regarding the application of the PRECIS tool in a cluster of RCTs belonging to...
The rationale behind this may lie in the pragmatic considerations involved in conducting clinical studies on medications that affect eosinophil counts. In other words, more patients may be included into a clinical trial if the definition of eosinophilia is lowered, and eventually, if benefit is ...
Pragmatic randomised controlled trials in psychiatry. RESULTS: Obstacles to performing pragmatic RCTs in psychiatry include the complexity of psychiatric interventions, the complexity of outcomes used in psychiatry... M Hotopf,R Churchill,G Lewis - 《British Journal of Psychiatry the Journal of Mental...
A total of 25 papers were RCTs, of which 8 (32%) received a strong overall rating. Data collection methods were moderately strong across all papers, with 60% of papers receiving a strong rating for this section. This is explained by the high percentages of papers reporting the use of ...
a Data extracted from figure. CI, confidence interval; GMT, geometric mean titre; IPV, inactivated poliovirus; NR, not reported; OPV, oral polio vaccine; SP, seroprevalence. Pragmatic review To support the interpretation of the findings of the systematic literature review, a pragmatic review was ...
There is an ongoing controversy over the relative merits of randomized controlled trials (RCTs) and non-randomized observational studies in assessing efficacy and guiding policy. In this paper we examine male circumcision to prevent HIV infection as a ca
The literature on giftedness in children is even more disparate. Therefore, in this systematic literature review, a pragmatic approach was taken. The decision was taken that studies were identified where the authors used the label ‘high attaining girls’. One of the aims of education is to ...