In a study by van der Ven et al., the predictive value of US for IA development within 1 year was studied in 159 patients with inflammatory arthralgia, without clinical synovitis, but with or without RA-related autoantibodies (ACPA-positive 15%; RF-positive 26.4%) [29]. Therefore, this ...
The mode of action of DT is summarised in Figure 1. Figure 1. Mode of action of diphtheria toxin (DT). (A) The receptor (R domain) of DT, shown here as green speres, binds to the membrane-anchored precursor of heparin-binding epidermal-like growth factor (proHB-EGF). (B) DT is...