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This reaction is regulated by the fusion histocompatibility locus (fuhc), which encodes a single, highly polymorphic, co-dominantly expressed gene (De Tomaso et al., 2005). Although we are beginning to understand the molecular mechanisms that underlie the allorecognition process (De Tomaso et al...
A mutation in a single gene causes the body to produce thick, sticky mucus that clogs the lungs and blocks ducts in digestive organs. What is a silent allele? A silent gene formally designates a rare (non-polymorphic, with frequency below 1%) recessive allele. Therefore, its presence can ...
Loss of heterozygosity (LOH) is a common genetic event in cancer development, and is known to be involved in the somatic loss of wild-type alleles in many inherited cancer syndromes. The wider involvement of LOH in cancer is assumed to relate to unmaskin
The major histocompatibility complex is a large locus on vertebrate DNA containing a set of closely linked polymorphic genes that code for cell surface proteins essential for the adaptive immune system. These cell surface proteins are called MHC molecules. ...
An annotated gDNA sequence is numbered so that cDNA and gDNA sites are interconvertable. A site map for PAHdb leads to a large array of secondary data (attributes): source of the allele (submitter, publication, or population); polymorphic haplotype background; and effect of the allele as ...
However, in this case these intriguing results cannot be attributed, in principle, to pre-existing polymorphic sites because control and experimental samples are descendants of the same male. We have to take into account that detection of transposition in Drosophila is not an easy task and that ...
Detection of MMR gene deletion can indirectly reflect the status of MSI. IHC, a method, is adopted to detect the expression of MMR protein which consists of hMLH1, hPMS2, hMSH2 and hMSH6 [12]. If the result shows that any of the above MMR protein expression is absent, it means MMR...
Correction:Isolation of sixteen autosomal loci and a sex-linked polymorphic microsatellite locus from the Milne-Edwards' sportive lemur (Lepilemuredwardsi)... Craul - 《Molecular Ecology Resources》 被引量: 11发表: 2009年 Sex-specific trans-regulatory variation on the Drosophila melanogaster X chromo...
It is then tempting to speculate that the 1831–1840. Indeed, the extent of sequence diver- gence and LD between the ZAL2 forms, revealing the suppression of recombina- stripe pattern might represent a male signalling display (Tuttle, 2003) more recently recruited onto the polymorphic Lake JI,...