"About 25% of people who harbor a pathogenic variant in a BRCA1 or BRCA2 gene have an increased susceptibility to those associated cancers compared to everyone else," she says, adding that she hopes for even better genomic screenings in the future. "If (clinicians) know that you're at...
Over the past three years, China has effectively responded to five global COVID waves and avoided widespread infections with the original strain and the Delta variant, which are relatively more pathogenic than the other variants. China has kept its severe COVID-19 cases and death rates among the...
What are phytopathogenic viruses? What is the pathophysiology of influenza? What is the pathogenesis of the Ebola virus? What is a communicable disease outbreak? What are viral oncogenes? What does ABS stand for virology? Is virology and immunology the same?
Molecular stratification can be performed based on (a) pathogenic mutations that affect a particular molecular pathway, (b) the identification of clusters of common genetic variants in genes associated with specific disease-associated pathways, or (c) biomarkers that indicate the level of function/...
The Omicron sublineage BA.5 is a more contagious variant. It spreads faster and has an improved capability to escape the immune system, experts said. 南非最新研究结果表示,BA.5变异毒株的R0值高达18.6,传播性是原始毒株的6...
What Causes Cancer in Women with a gBRCA Pathogenic Variant? Counselees' Causal Attributions and Associations with Perceived Control Laypersons have a strong need to explain critical life events, such as the development of an illness. Expert explanations do not always match the beliefs o... F ...
Guillain-Barré syndrome (GBS) is a disorder in which the body’s immune response, typically to an infection, causes nerve damage. These three forms of…
Laypersons have a strong need to explain critical life events, such as the development of an illness. Expert explanations do not always match the beliefs of patients. We therefore assessed causal attributions made by women with a pathogenic germline variant in BRCA1/2 (gBRCA1...
Further, a larger proportion of young women with breast cancer carry pathogenic variants in cancer predisposition genes such as BRCA1/2, compared to late-onset breast cancer [11,12,13]. The other important factor is that young women are often not included in breast cancer screening programs ...
However, DNA sequencing can only detect a genomic variant that alters or removes a splicing site. Conversely, RNA sequencing detects the fusion of exon 13 to 15 because this is the convergent result of any altered splicing mechanism or deletion. In addition to pre-analytical considerations, such...