A nucleoside by definition has two distinct parts: a cyclic, nitrogen-rich amine called a nitrogenous base, and a five-carbon sugar molecule. The sugar molecule is either ribose or deoxyribose. When a phosphate group becomes hydrogen-bonded to a nucleoside, this accounts for the entire difference...
Gemcitabine hydrochloride is a nucleoside homologue and a cell cycle-specific anti-tumor drug. It mainly kills cells in S phase (DNA synthesis), and also blocks the transition process of cell proliferation from G1 to S phase. It is metabolized by nucleoside kinases into active nucleoside diphosph...
For the formation of DNA strand, huge amount of energy is required. We know that ATP (adenosine triphosphate) is the main energy molecule for... Learn more about this topic: DNA: Chemical Structure of Nucleic Acids & Phosphodiester Bonds ...
What is a difference between DNA replication and RNA transcription? The difference between ATP and the nucleoside triphosphates used during DNA synthesis is: A. The nucleoside triphosphates have the sugar deoxyribose; ATP has the sugar ribose. B. Triphosphate monomers are active in the nucleoside tri...
The delity o a DNA polymerase is the result o accurate replication o a desired template. Speci - cally, this involves multiple steps, including the ability to read a template strand, select the ap- propriate nucleoside triphosphate and insert the correct nucleotide at the 3´ primer terminus...
Adenosine, a naturally occurring endogenous metabolite formed by the degradation of adenosine triphosphate (ATP), not only terminates but also helps define the mechanism of several arrhythmias discovered in 1929. ATP gets metabolized into adenosine after intravenous administration and is used to treat car...
This product is a nucleoside reverse transcriptase inhibitor related to thymidine. It is converted into triphosphate in stages within the cell, and this salt can terminate the DNA synthesis of retroviruses (including HIV). This termination is accomplished through competitive inhibition of reverse ...
Ganciclovir is a potent inhibitor of herpes viruses, including CMV. It is a nucleoside analogue that suppresses the replication of herpes viruses and functions as a virustatic agent. Ganciclovir has been used systemically, in the form of intravitreal injections and implants for CMV infections of ...
What is the difference between a nucleotide and a nucleoside? What do all amino acids have in common? What is the role of nucleotides in DNA? Which types of nitrogenous bases are adenine and uracil, and where are they found? What does albumin have that ribose doesn't?
What is the structural difference between a nucleotide (NTP), a deoxynucleotide (dNTP), and a dideoxynucleotide (ddNTP). Nucleoside: A pentose sugar and a nitrogenous base bind together to form a nucleoside...