Immunostaining demonstrates that under (A) normal, healthy, conditions nerve fibers do not enter the tendon proper (intra-fascicular matrix). In painful tendinopathy (B) pathological ingrowth of sensory nerves is consistently observed in the intra-fascicular matrix. Nerve ingrowth has been ...
CRTH2 is a critical activator of the polarized T helper response. In the chronic phase of the disease, on the contrary, basophils showed a progressive increase in levels with the improvement of the humoral immune response, perhaps related to the production of IL-4 by these cells [1]. In ...
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The perception of bronchial asthma has fundamentally changed during the last decade. Consequently, the Global Initiative for Asthma (GINA) suggested a new definition of asthma: “Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation. It is defined by the history of r...
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