TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex. Nat. Genet. 36, 618–623 (2004). CAS PubMed Google Scholar Ye, J. Z. et al. POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex. Genes Dev. 18...
Given the current insatiable demand for battery metals, it is possible that in the event a massive discovery is made, that the project may be deemed a strategic asset and perhaps expropriated. It would be prudent to recognise this legal risk and mitigate it where possible. Having worked on p...
Research in the authors' laboratories is supported by grants from the US National Institutes of Health (DP2CA195767 and DK102562 to A.S., and AG038677 to E.L.D.) and the American Cancer Society (RSG-14-186) to E.L.D. A.S. is a Pew-Stewart Scholar, a Damon Runyon-Rachleff gra...
Research on why quality improvement collaboratives succeed or fail has produced the following list of critical success factors: taking a whole-system approach, selecting a topic and goal that fits with organizations’ priorities, fostering a culture of quality improvement (e.g. that quality is every...
A neuroradiologist is a medical doctor who has special training in imaging procedures (diagnostic neuroradiol- ogy) and therapeutic procedures (interventional neu- roradiology) in the brain and spine, as well as the asso- ciated blood vessels and skeletal elements. During their training, neuro...
He smiled. “Believe it or not, my sister is a doctor at an English-speaking hospital there. If you want, I’ll make a call right away and we’ll try and get your mom transferred (转移).” A few days later I sat in the living room with my daughter as she finished the last of...
It is widely accepted that intellectual property legal requirements such as patents and data exclusivity can affect access to medicines, but to date there has not been a comprehensive review of the empirical evidence on this topic. The World Trade Organi
i know jump i know love is a hot i know my dad wanted i know my grandmother i know that no good i i know that hard i know that i freaked i know that they i know that this aint i know the angles i know the feeling i know their ways i know this is out of i know what you...
Physiological resilience or durability is now recognised as a determinant of endurance performance such as road cycling. Reliable, ecologically valid and s
However, it is becoming clear that it is difficult to integrate and interpret these data and to translate them into treatments. This difficulty is compounded by the recognition that cancer cells evolve, and that initiation, progression and metastasis are influenced by a wide variety of factors. ...