Individual point mutations are rare (1 /megabase), so it's necessary to sequence each gene as many as 500 times to make sure the mutations are real. This is called increased sequencing depth. In cancers induced by mutagens, there are roughly 100 mutations/Mb.[5]In other cancers, such as...
Some so-called mutation "rates" in cancer genomic studies are simply the numbers of accumulated mutations per megabase of DNA in a tumor at the time of analysis. Don't jump to conclusions until you know what type of "mutation rate" is being described. The moral here ...
Next up is a honey tamed Direbear. Only really need the Theri technically. Oh and Allos are my next target. No access to any of the weirder ones yet. Theri tamed first? I guess you're one of those people that enjoy playing on a x1000 taming server and have a megabase ...
into a human virus, hepatitis delta virus HDV [99], which may have acquired genetic information for a protein from the host, because HDV antigens are related to a human protein [12,17,18,36]. HDV is the only virus known to be a catalytic ribozyme and pathogen in humans. Why is there...
Asked how mature the field of genome assembly is, Ian Korf at the University of California, Davis, compares it to a teenager with great capabilities. “It's got bold assertions about what it can do, but at the same time it's making embarrassing mistakes,” he says. Perhaps the biggest ...
Beside this evolutionary theory, there is no doubt that extracellular vesicles (EVs) represent the smallest cell-like entities surrounded by a lipid structure. The biology of EVs has been widely documented over the last decade, mainly in terms of their origin, composition, diversity and biological...