When colonoscopy is used as the reference standard, simulated flexible sigmoidoscopy has a sensitivity for detecting any advanced colonic neoplasm throughout the colon of 70% to 86% (SOR: A, systematic review of cohort studies) and a single stool guaiac test is...
Occasionally, perforation affects the bowel and other parts of the intestine and may require colostomy, in which part of the large intestine is brought into the wall of the abdomen and waste material is excreted into a bag outside the body. This is generally temporary. After surgery, the ...
Inflammatory bowel disease (IBD) is an umbrella term most often used to describe two gut disorders—ulcerative colitis(UC) andCrohn’s disease. As you can probably tell from the name, IBD involves significant inflammation in the small or large intestine, or both. Depending on the severity, IBD...
et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature 504, 446–450 (2013). Article CAS PubMed Google Scholar Thorburn, A. N. et al. Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites...
TheDrosophilagut shares a similar structure to the mammalian gut TheDrosophilagut is subdivided into the foregut, midgut, and hindgut, which broadly represent the esophagus, small intestine, and large intestine in mammals (Fig.2). TheDrosophilagut is composed of an epithelial layer surrounded by vi...
It is consistent with previous reports in adult patients (Ott et al., 2004) and with preclinical studies demonstrating elevated murine Th1 responses induced by human stool microbiomes rich in oral taxa (Atarashi et al., 2017). The extension of this finding to a large pediatric UC cohort is ...
The first objective of infant formulas is to ensure the healthy growth of neonates and infants, as the sole complete food source during the first months of life when a child cannot be breastfed. Beyond this nutritional aspect, infant nutrition companies also try to mimic breast milk in its un...
This modulation is more intense in individuals with a higher level of oxidative stress and an inflammatory state. Furthermore, this effect is reduced when the different phytonutrients are used in isolation [42]. On the other hand, in large observational studies, it has been seen that the ...
Second, at present, the gut microbiome is also primarily studied by the use of stool bacterial communities as a proxy. Stool samples are broadly representative of colonic luminal bacteria; however, some communities of bacteria may be overlooked including those found in the small intestine or ...
Non-alcoholic fatty liver disease (NAFLD) is a serious health problem due to its high incidence and consequences. In view of the existing controversies, new therapeutic options for NAFLD are still being sought. Therefore, the aim of our review was to eva