Finally, a new report provides a glimpse into the potential regulation of CENP-A through specific post-translational phosphorylation, suggesting a broad level of control through histone tail modifications.M.MitchellSmithSDOSCurrent Opinion in Cell Biology...
What is the "brain" of a tree? What is \textbf{Histone}? What is SIBO? What is a comminuted fracture? What is Zugunruhe? What is a kinetochore? What is an osmoconformer? It is the what that gives bones its stiffness? What is a contig?
Example of it is when flipping a coin. When we consider the head as highly significant, the other one, which is the tail, would be considered not. That is a one-tailed test. On the other hand, if we consider both the tail and the head as a significant factor to the test, then ...
Chromatin immunoprecipitation (ChIP) offers an advantageous tool for studying protein-DNA interactions. It can be used for determining if a specific protein binds to a particular sequence of a gene, such as the target sequence of a transcription factor or to compare the level of histone methylation...
Epigenetic modulations such as DNA methylation, post-translational modifications of histone tail, and non-coding RNAs, help regulate all biological processes and are implicated in a wide range of human disorders [78]. DNA methylation and histone modifications are associated with inflammatory complexes su...
Almost all eukaryotic mRNAs are polyadenylated, with the exception of animal replication-dependent histone mRNAs. What is the major Deadenylase complex that shortens poly A in the cytoplasm? 3. For example, both the Pan2-Pan3 and the Ccr4-Caf1 deadenylase complexes, the two main deadenyl...
T cells learn to discriminate self from non-self during development in the thymus, and while their primary function as naive T cells is to survey the body for foreign antigen, they maintain a lifelong relationship with the self-immunopeptidome [1], [2]. Interestingly, the range of affinities...
Histone deacetylase (HDAC) inhibitors have been demonstrated to be beneficial in animal models of neurodegenerative diseases. Such results were mainly associated with the epigenetic modulation caused by HDACs, especially those from class I, via chromatin
Preparation of chitosan self-aggregates as a gene delivery system.J Control Release. 1998;51:213–220. PubMed CAS Google Scholar Balicki D, Beutler E. Histone H2A significantly enhances in vitro DNA transfection.Mol Med. 1997;3:782–787. PubMed CAS Google Scholar Balicki D, Putnam CD,...
What is a z- test?Answer and Explanation: A z-test is used in statistics to determine if the difference between a sample and population mean are statistically significant or due to random chance. This helps researchers assess whether the results can be trusted, or if there was a flaw in ...