differs. The specific geometry can be described in terms of the wrapping vector containing the length (the tube’s circumference) and a helix angle a (ranging from 0 to 30°) and so the two numbers (n,m) are used for SWCNT definition. The helix angle in terms of (n,m) is: ...
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A conformational analysis using molecular simulation. Keller B,Gattin Z,van Gunsteren WF. Proteins Struct. Funct. Bioinf . 2010Keller B, Gattin Z, van Gunsteren WF (2010) What stabilizes the 314-helix in b3-peptides? A conformational analysis using molecular simulation. Proteins: Struct Funct ...
C-terminal to its alpha helix and joined by an extended linker, a ZnF domain in Sgf11 binds Ubp8 close to its catalytic domain, forming the catalytic lobe of the DUB module. The N-terminal region of Sgf73 is located between the two lobes and makes extensive contacts with the three ...
Specifically, the alpha1-extension helix of H2A.Z appears to be important for proper recruitment and orientation of RNF168, facilitating the setting of the ubiquitin modification that subsequently recruits different HR pathway factors to DNA damage sites. It remains puzzling that H2A.Z seems to be...
Autophagy is induced in response to various metabolic stresses, and engulfs a por- tion of cytoplasm for degradation, thereby acting as a cell survival mechanism. Autophagy also functions as a qual- ity control system by selectively removing misfolded and aggregate-prone proteins, and damaged or ...
The PD is a conserved 128 amino-acid DNA-binding domain composed by two helix-turn-helix motif subdomains, PAI and RED.29 The OP and HD exert positive or negative regulation of transcription depending on the cellular context and availability of cofactors. Most of the current insight regarding ...
The PD is a conserved 128 amino-acid DNA-binding domain composed by two helix-turn-helix motif subdomains, PAI and RED.29 The OP and HD exert positive or negative regulation of transcription depending on the cellular context and availability of cofactors. Most of the current insight regarding ...
To shed light on the mechanistic basis of this difference, we first need to understand the general molecular mechanism by which directional movement is generated driven by the energy originating from NTP hydrolysis. As one would expect, the elements involved in this essential NTPase activity are ...
Vacuole is an important subcellular compartment serving as a temporary reservoir for many ions, including Pi (Pratt et al., 2009). However, the proteins responsible for the transport of Pi across tonoplast and the underlying molecular regulatory mechanisms remain elusive. Two rice genes of the SPX...