Self-care is the most important aspect of kidney care. A patient’s ability to understand his/her health needs, make healthy choices, and feel safe and respected in the health system, and psychosocial support are important to promote health decision-making (Fig.4). Communication should start f...
Artificial intelligence (AI) is a data-driven method. In other words, after being trained with many samples, an AI model can automatically select the optimal feature pattern to accurately predict the novel samples. Thus, when AI methodology is used to analyze medical images of PCa, it can min...
Stage 2 CKD: Mild loss of kidney function, eGFR 60-89. Stage 3a & 3b CKD: Mild to severe loss of kidney function, eGFR 30-59. Stage 4 CKD: Severe loss of kidney function, eG FR 15-29. Is GFR 94 normal? Results. A GFR of60 or higher is in the normal range. A GFR below 60...
<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d5165680e122">Heart Failure (HF) is one of the leading problems in cardiology practice today. Acute decompensated heart failure (ADHF) is a significant caus
Although this phenomenon is not common, it has therapeutic significance. And the study of Abida et al. showed that MSI-H/dMMR patients with bladder cancer have good prognosis for the anti-PD-1/PD-L1 treatment [55]. Cholangiocarcinoma Goeppert et al. [56] have found that MSI-H can be ...
[52]. A study based on the EQUAL study (n = 1334) showed that the risk of PEW in CKD patients with eGFR < 20 ml/min increases substantially with age and is commonly characterized by muscle wasting [53]. Hence, aging adds up as a contributing factor to the etiology of ...
In this study, assessment of immune score was a better predictor of tumor recurrence (HR = 0.64; P < 0.001) than TNM classification. However, the immune infiltrate is highly heterogeneous in a tumor, and quantification is observer-dependent. To simplify and harmonize the quantification of immune...
In contrast, the second mechanism by which AVP may exert a detrimental influence on kidney function and thus GFR (or eGFR) is much more indirect. It is common to all forms of chronic kidney disease whatever the initial cause of the disease, and therefore it should also occur in ADPKD, alt...
Further, a larger proportion of young women with breast cancer carry pathogenic variants in cancer predisposition genes such as BRCA1/2, compared to late-onset breast cancer [11,12,13]. The other important factor is that young women are often not included in breast cancer screening programs ...
HER2 lacks of a known exogenous ligand and it is transactivated by the interaction with other HER family members (EGFR or HER3 overall) or other tyrosine kinase receptors. Its activation leads to a complex cascade of transduction events within the cytoplasm, that converge on two fundamental signa...