What's New in Genetic Testing for Cancer Susceptibility? The advent of next-generation sequencing, and its transition further into the clinic with the US Food and Drug Administration approval of a cystic fibrosis assay in 2013, have increased the speed and reduced the cost of DNA sequencing. C...
BA.1 wound up acquiring 60 mutations that are not found in the ancestral SARS-CoV-2 that first surfaced in Wuhan, China. Among them are 32 genetic changes located specifically in the virus’s iconic spike protein,...
Genotyping is the technology that detects small genetic differences that can lead to major changes in phenotype, including both physical differences that make us unique and pathological changes underlying disease. It has a vast range of uses across basic sc...
In Part I the chemistry of enzyme assays is discussed, in Part II the assays used in the context of genetic selection are covered, and in Part III multisubstrate as- says for biochemical characterization of enzymes are discussed. Before even starting into t...
Thus, this approach appears to make sense; it is not coincidental but strongly supports the notion that transcriptomes harbor the molecular genetic code for cell type identity. However, there are several challenges that must be surmounted to arrive at a complete and accurate evolutionary definition ...
What is tumor mutation load? Why does the immune repertoire matter? Cancer is a genetic disease with mutations that cause a change in regulatory processes causing cells to grow out of control and become invasive (1). Some of...
Dec 16, 2021 The Philadelphia Inquirer Philadelphia’s ability to track COVID-19 variants — and the nation’s — is hobbled by a lack of resources Dec 9, 2021 MedCity News As genetic testing expands, evidence and awareness needed to spur adoption Dec 6, 2021 Leaps.org Researchers Are Dis...
Poly-A is a repetitive sequence of adenine nucleotides added posttranscriptional to the 3’-end of a eukaryotic mRNA molecule.
The evolution of plants to efficiently transport water and assimilates over long distances is a major evolutionary success that facilitated their growth and colonization of land. Vascular tissues, namely xylem and phloem, are characterized by high specia
Introduction It is now recognized that a large number of arthropods are host to sel®sh genetic elements that distort the sex ratio (Hurst et al., 1996). These are of two types. First, there are the cases of meiotic drive associated with sex chromosomes. Here, one of the sex ...