Thepromoter, a DNA sequence that liesupstreamof the RNA coding region, serves as an indicator of where and in which direction transcription should proceed. The promoter is not actually transcribed; its role is purely regulatory. While promoters vary tremendously among eukaryotes, there are some comm...
The RNA promoter provides its function by providing a binding site for RNA polymerase I, the enzyme that transcribes rRNA, as well as associated transcription factors. The promoter sequence on the DNA is different than most genes, which use a thymine and adenine series of nucleotides called a ...
The RNA promoter provides its function by providing a binding site for RNA polymerase I, the enzyme that transcribes rRNA, as well as associated transcription factors. The promoter sequence on the DNA is different than most genes, which use a thymine and adenine series of nucleotides called a ...
A search for doxycycline-dependent mutations that increase genes A P-type transposable element called has been engineered with a doxycycline-inducible promoter directed out through the 3' end of the element. Insertion of near the 5' end of a gene often yields doxycycline-dependent overexpression of...
What genes are involved in DNA repair? What does a DNA library consist of? What two cell division processes use DNA replication? Who proposed the semiconservative method of DNA replication? What is a promoter in DNA replication? What feature of DNA structure allows it to replicate?
(d) How is information integration at gene regulatory sequences achieved? Genes Genes are units of DNA that serve as discrete pieces of information from the cell, which information can be used to create a certa...
PromoterThe human genome (see Box 1.1) is composed of some 20,000 protein-coding genes and approximately the same number of genes for non-coding RNAs (ncRNAs), being used as a structural backbone of ribosomes (ribosomal RNA (rRNAs)), adaptor molecules in protein translation (transfer RNA (...
What is an operon? An operon is a set of genes that are regulated together and controlled by a single promoter. This unit of genetic material consists of a promoter, operator, and structural gene(s) that are transcribed into mRNA together. Operons are commonly found in prokaryotic organisms ...
CD127 is a type I transmembrane glycoprotein also known as IL-7 receptor α chain (IL-7Rα). Foxp3 binds to the promoter of CD127, and its unique forkhead DNA-binding domain is close to the C terminus of the protein, which inhibits the transcription of CD127 [36]. Seddiki et al. ...
Some genes that encode housekeeping proteins are transcribed all the time; other genes are transcribed only in response to a signal from the cell’s environment. As you likely know, RNA transcription is initiated from promoter elements that target transcription factors to the DNA template. RNA ...