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Longitudinal analysis when the experimenter does not determine when treatment ends: what is dose- response? Clin Psychol Psychother. 2003;10:352-360.Feaster, D. J., Newman, F. L. & Rice, C. (2003). Longitudinal analysis when the experimenter does not determine when treatment ends: What ...
Implicit in optimal loading is the need to monitor the response to load, but what constitutes a normal response to loading? And does it differ among tissues (e.g., muscle, tendon, bone, cartilage) and systems? In this paper, we discuss the “normal” tissue response to loading schema ...
Risk of bias assessment diagram Full size image Primary outcomes VAS score VAS score at 3 months Conventional meta-analysis: two articles, which included three experimental groups with a total of 33 patients, provided information on VAS improvement at a low dose; one literature with two experimenta...
The concept of hormesis, or low-dose U-shaped responses, is now well established in toxicology and pharmacology but requires development in medicine and therapeutics. In doing so, care must be taken to not confuse metaphorical and chemical uses of the term hormesis. Low dose, continuous adaptive...
Assessment and evaluation Delegation Goal setting Managing appointments Meeting deadlines Multitasking Prioritizing Resource management Scheduling Organizational Skills They say entropy is the natural state of things. This could be true, but only up to a point. The point at which yourorganizational skillsco...
Part of the COVID-19 illness is viral lung infection (viral pneumonia). A small number of viral pneumonias can also develop a bacterial infection within the lung. The addition of the bacterial infection on top of the viral infection is called a secondary bacterial infection. ...
•Whatistheminimumfrequency(ifvolumeishelpconstant)requiredtodecreasemortality?METHODS •Forty-fourstudiespublishedbetween1966andJuly2000.RESULTS •Alinearinversedose-responserelationshipin34ofthe44studies.•Remaining10studies,5showedathresholdeffectand5showednoeffect.•24ofthe44studiesincludedwomen.•...
The dose–response relationship or hazard assessment is determined by epidemiologists and experts in human susceptibility and pathogen virulence. The FSO is the common parameter between these two different areas of expertise. The regulatory process requires establishment of a specific criteria, a bright ...
Challenging dose-response dogma: hormesis presents a good model for toxicological risk assessment--and it's not homeopathy The central pillar upon which toxicological assessments are built is the dose-response relationship. But reliance on theoretical prediction models for dose response creates a wolf-...