In the next sections below we discuss the current state of knowledge on a particular family of pore-forming proteins, namely, the RTX pore-forming toxin family, which is as large as it is unknown in many aspects. We also summarize recent information from our own laboratory on pore formation...
3.1. Clinical Considerations for a Patient with Thrombocytopenia Receiving Chemotherapy Whilst chemotherapy use is an established aetiology for thrombocytopenia whether by inhibition of platelet production, upregulation of platelet destruction or by increased immune-mediated clearance, alternative causes must be...