CAS Numbers CAS Numbersare up to 10 digits long using the format xxxxxxx-yy-z. They are assigned to a compound as the CAS registers a newcompound. The number has no significance to the chemistry, structure, or chemical nature of the molecule. The CAS Number of a compound is a useful wa...
When a bacterium is infected by a virus, it uses a Cas nuclease to snip off a piece of viral DNA known as a protospacer. This fragment is stored in the bacterial genome with fragments from other viruses that have previously infected the cell - an immune memory. These viral spacer ...
3., 4. This is somewhat surprising given the foundational position of complexes such as bis-benzene chromium in our understanding of transition metal chemistry, and its role in chemistry coursework, along with that of “piano-stool” arene complexes in medicine.5 Just a handful of simple, ...
It reacts with trimethylchlorosilane to produce tris(trimethylsilyl)amine, in which the coordination number of nitrogen is 3, and the spatial configuration is a plane regular triangle. In organic synthesis or pharmaceutical synthesis, lithium bistrimethylsilylamide is usually used as a strong base to...
Trimethoprim alone is mainly used for the treatment and prophylaxis of urinary tract infection. Co-T, on the other hand, has both these indications and a very broad range of other uses. A number of other trimethoprim–sulfonamide combinations have been marketed over the years, including trimethopr...
Synthetic Chemistry Methodology Solid-phase Synthesis Introduction In drug discovery, the traditional Design-Make-Test-Analyze (DMTA) cycle is undergoing substantial changes, driven by the incorporation of novel artificial intelligence approaches [1]. Within the “Design” phase of DMTA,de novodrug desig...
Cancer is an extraordinarily complex disease. Methods that are commonly used in physics can reduce the complexity of cancer to a manageable set of underlying principles and phenomena. In particular, Transport OncoPhysics views cancer as a disease of multiscale mass transport deregulation involving the...
Ampeater Music is a website devoted to bridging the gap between unsigned (or just plain underexposed) artists and music lovers everywhere. Every day we feature a different artist on what we call The Ampeater Review. Each fea
Mankind has always relied on “practical wisdom” in the sense of Aristotle to change people and society. However, practical wisdom is difficult to accumulate and pass on from generation to generation. Therefore, although “natural engineering” that is
Information has become in this way the key concept of modern biology, but also the object of a fierce controversy. The reason is that information, heredity and natural selection simply do not exist in the world of chemistry, and this creates a contrast with the idea that “life is chemistry...