Finally when a distinct and highly variable apolipoprotein (a) joins apoB on LDL, an atherothrombotic lipoprotein (a) is formed that is cleared less efficiently and can further augment the LDL particle burden. These important members of the proteome are reviewed....
Lately, measuring the concentration or number of lipoprotein particles has been found to be useful to assess risk. Examples of such measurements are measurements ofLDL particle number (LDL-P),apolipoprotein Band Lp(a). It has been known for some time that Lp(a) is a decisive risk factor for...
Ohrvik J, et al. Concentration of apolipoprotein B is comparable with the apolipoprotein B/apolipoprotein A-I ratio and better than routine clinical lipid measurements in predicting coronary heart disease mortality: findings from a multi-ethnic US population. Eur Heart J. 2009;30(6):710–7. ...
BHT is odorless, odorless with good thermal stability.BHT, also known as dibutylhydroxytoluene, is a lipophilic organic compound, chemically a derivative of phenol, that is useful for its antioxidant properties.Fig 1. Chemical structure formula of BHT...
Along the same lines, it is also possible that HRT benefits mood and cognition in the context of normal aging, but not in women already at risk for developing AD. As we move closer to personalized medicine, the use of genetic, protein, and imaging biomarkers to pre- dict healthy brain ...
Allan Sniderman who has been an advocate for using apolipoprotein B for risk assessment [8]. His rationale was that, as there is one molecule of apo B per each LDL particle and the LDL half-life in plasma is much longer than that of the other apo B containing lipoproteins, the ...
Liver fat storage, also called hepatic steatosis, is increasingly common and represents a very frequent diagnosis in the medical field. Excess fat is not without consequences. In fact, hepatic steatosis contributes to the progression toward liver fibrosi
Such approaches examine whether test statistics for a group of related genes have a consistent yet moderate deviation from chance (Wang et al., 2010). The underlying rationale is that genetic variants are unlikely to act randomly, but multiple genes work together in functional gene sets based on...
Regarding the genetic study,apolipoprotein E(APOE) is a key protein in CAA pathophysiology that regulates lipid metabolism [3]. TheAPOEgeneε2andε4allele carriers increase the risk of CAA-related ICH compared toAPOE ε3, which is the most commonAPOEtype [10]. In addition, the most common ...
(BECs; cholangiocytes). Hepatocytes perform most of the liver functions, while bile ducts formed by cholangiocytes transport bile acid produced by hepatocytes to the gallbladder. For an overview of liver architecture, see Fig.1. The liver is a largely quiescent organ, and hepatocytes are ...