Because most SSRI and SNRI receptors are found in the central nervous system (CNS), GI tract, and blood vessels, the clinical signs of toxicity with these drugs are neurological, gastrointestinal, and cardiovascular. CNS depression, agitation, tremors, and seizures are the most common signs of ...
SSRIs first came onto the market in the late 1980s, with the first of these drugs — fluoxetine (Prozac®) — beingapprovedin 1987 by the Food and Drug Administration (FDA). Compared to other antidepressants, SSRIs havefewer side effectswhile still being effective. SSRIs arebelievedto work...
NSAIDs are drugs that treat pain as well as fevers. Here’s what you should know about how NSAIDs work, possible side effects and risks, and alternatives if you can’t tolerate them.
Although similar to fibromyalgia drugs in effectiveness, TMS does not carry any negative side effects. SLIDESHOW What Is Fibromyalgia (Fibro)? Symptoms, Causes, Helpful Treatments See Slideshow What other therapies can help relieve fibromyalgia symptoms? Cognitive behavioral therapy (CBT): CBT is ...
Some people believe that brain zaps are a sign of traditional withdrawal, similar to what you’d experience with drugs or alcohol—and they get worried that they’ve become too dependent or “addicted” to the antidepressant itself, Dr. Gold explains. However, that’s not the case—your brai...
However, new formulations of established dopaminergic drugs, device-aided applications, and new drug targets for the treatment of motor fluctuations in advanced stages have further improved the care of patients with PD. With nearly 150 registered clinical trials for disease-modifying and symptomatic ...
Individual characteristics, such as polymorphisms of the gene encoding the 2D6 subunit of cytochrome P450, may affect the metabolism of the SNRI; while, the combination with other drugs may lead to an increased risk of iridocorneal angle closure, and may further exacerbate other mechanisms. ...
For what they're worth, here are some suggestions. First, so long as you can afford it, stick with the long, messy business of finding the right drugs for you. Each successive bout of depression I've had has been worse than the one before. Knowing that the next time will be worse,...
What are the different types of neurotransmitters? What are the chemical classes of neurotransmitters? How do neurotransmitters work as chemical messengers? How do you boost neurotransmitters? Which neurotransmitter system do many stimulant drugs affect? What are the two most common neurotransmitters? What...
Opioids are the mainstay of cancer pain treatment; however, a new group of therapeutics called coanalgesic drugs has been introduced to pain treatment. These coanalgesics include gabapentinoids (gabapentin, pregabalin), antidepres- sants (tricyclic antidepressants, duloxetine, and...