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Importantly, the kinase domain in exon 9- mutant KIT is essentially the same as in wild-type KIT, and this influences inhibitor sensitivity. Interestingly, these mutations occur in tumors arising in the small and large intestine, but are very rarely seen in gastric GISTs. Mutations in the ...
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In addition to assessment of GMB composition between AD mouse models and wildtype mice, several studies have altered the GMB in AD mouse models, primarily by using antibiotics (abx) or housing mice in germ-free environments wherein the mice are devoid of microbes and thus do not develop a G...
This chapter summarizes the methodological issues and empirical findings on the acuity of perception of interoceptive information, dubbed interoceptive accuracy. Both homeostatic (classic visceroceptive channels, thermosensation, itch, pain, affective to
Although geneticallyD. r. bugensisis only slightly different fromD. rostriformisand thus likely does not qualify as a separate species, they occupy drastically different habitats. While all populations ofD. rostriformisare brackish water organisms inhabiting the profundal areas of the Caspian Sea wi...
ACE2 is mainly expressed in the human heart, kidney, lungs, liver, intestine, and testis [17]. More recently, it was found that ACE2 is also expressed in human ovaries, oocytes, and endometrial tissue, although its functional role is still unclear [18,19,20]. Emerging studies in the la...
Over the last decade the number of patients undergoing transplantation has increased. At the same time, effective peri- and postoperative care and better s
International Journal of Molecular Sciences Review What Do We Know about Opioids and the Kidney? Mary Mallappallil *, Jacob Sabu, Eli A. Friedman and Moro Salifu Department of Internal Medicine, State University of New York at Downstate, Brooklyn, New York, NY 11203, USA; sabujacob111@gmail...
Thus, does a long-lived population of mTreg cells exist? In this review, we would like to discuss the concept of regulatory memory and in which tissues mTreg cells can perform their functions. Box 1. Regulatory T cells. Regulatory T cells (Tregs) are a specialized subset of ...