Antipsychotic drugs: prolonged QTc interval, torsade de pointes, and sudden death. Am J Psychiatry.2001;158:1774-1782.Google Scholar 53. Ray WA, Meredith S, Thapa PB, Meador KG, Hall K, Murray KT. Antipsychotics and the risk of sudden cardiac death. Arch Gen Psychiatry.2001;58:1161-...
delamanidtuberculosisBedaquiline and delamanid used to treat extensively drug-resistant tuberculosis are known to cause prolonged QTc. Two children with extensively drug-resistant tuberculosis were put on bedaquiline and delamanid and had prolonged QTc on the Bazett formula but normal QTc by the Fridericia...
Electrocardiographic QTC interval: short-term weight loss effects. Int J Obes Relat Metab Disord 1997; 21 (2): 1-10. 57. De Fonzo R, Soman V, Sherwin R, Hendler R, Felig P. Insulin binding to monocytes and insulin action in human obesity, starvation and refeeding. J Clin Invest 1978...
The presence of coronary artery disease does not appear to have much impact on the ECG intervals. However, mean and median values for the PR, QRS, and QTc intervals do not differ greatly from published normals.Table 1, abstract 230Mean Rate (SD; Range)Mean PR Interval, ms (SD; Range)...
If QTc prolonged on EKG, an alternate drug may be needed. Drug interaction: Conivaptan: could increase concentration ofCYP3A4 substrate. ESRD: Transdermal patch suggested to not be used with ESRD (MW 336; lipophilic; Vd 4 L/kg). CKD: Reduce dose by 50%; limited information on other ...