Covering both basic science research and clinical investigations, BoneKEy will provide the bone field with an online platform for scientific exchange and community growth based on expert scientific contentSeiji FukumotoFukumoto S (2014) What can FGF23 do without klotho? Bonekey Rep 3:551.
FGDO FGDP FGDS FGDSM FGDT FGDTLC FGDY FGE FGEA FGEAB FGEB FGebV FGEC FGECL FGEDG FGEF FGEHF FGEI FGEIS FGEKS FGEN FGEO FGEOL FGEP FGER FGES FGETS FGEW FGEX FGF FGF-1 FGF-2 FGF-5 ▼ Complete English Grammar Rules
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It is noteworthy that studies have shown that FGF dysregulation can create increased susceptibility to the development of ASD, contributing to the disruption of immune and neuronal functions associated with the disorder. ASD does not have a simple or single neuroanatomical phenotype that indicates ...
High expression levels of a cadre of such genes like SOX2, growth differentiation factor-3 (GDF3), TDGF, EBAF, and FGF4 have been observed in embryonal carcinoma, but not in seminoma. Synchronous Seminoma in Abdominopelvic and Inguinal Testes: A Rare Presentation with Unusual Morphology A ...
In addition, FGF-23 plays an essential role in regulating the expression of the OPG gene [14]. Studies have found that FGF23 is elevated during critical illness, accompanied by bone loss [15]. The loss of bone can promote glucose intolerance or systemic inflammation, which can aggravate bone...
Ongoing cancer research continues to identify newer, less toxic, and more effective cancer treatments. Visit the National Cancer Institute (NCI) to see a list of ongoing clinical trials. Sources: This tool does not provide medical advice.See additional information:...
Recent stud- ies have reported that FGF23 may be a novel target for early diagnosis of renal insufficiency and cardiovascu- lar disease, and may also be a potential therapeutic tar- get for patients with chronic kidney disease [18]. Some scholars even believe that elevated serum levels of ...
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The negative outcome on bone health is probably also related to the fact that high doses of vitamin D increase FGF-23 concentration, sclerostin and Dickkopf-1 (DKK-1). The sclerostin and DKK-1 increase inhibits Wnt signaling, and might trigger an upregulation of 1,25-dihydroxyvitamin D3 ...