Stimulation of astrocyte fatty acid oxidation by thyroid hormone is protective against ischemic stroke-induced damage. J Cereb Blood Flow Metab. 2017;37(2):514–27. Article PubMed Google Scholar Winstein CJ, Stein J, Arena R, Bates B, Cherney LR, Cramer SC, et al. Guidelines for adult ...
This strikes most as such an obvious statement that follow-up questions like "what does compute mean in that phrase, exactly?" are met with a sigh that speaks quite clearly --- "Please keep the philosophy aside, we are trying to do actual science here." But my day job has been in ex...
The discovery of the lactate shuttle (LS) mechanism may have two opposite perceptions, It may mean very little, because the body normally and inexorably uses the LS mechanism. On the contrary, one may support the viewpoint that understanding the LS mechanism offers immense opportunities for unders...
Furthermore, rats that received LPS displayed enhanced recovery in rehabilitative training and a paradoxical reduction in microglial and astrocyte density around the lesion site [83]. Similar findings were observed in the present study; although not statistically significant, FMT treated rats displayed ...
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Results:They were high rates of anxiety disorders in the grandchildren (mean age 12 years) with two generation of MDD. Grandchildren with both a depressed parent and grandparent as compared with those where the parent was not depressed had over a four fold increased risk of anxiety and over ...
mean by this is that our most refined neural wetware runs a relatively simple GABA-glutamate-glutamine metabolic cycle on an elaborate tripartite synaptic hardware; it is a co-op where three different kinds of mitochondria, those optimized by interneuron, pyramidal cell, and astrocyte, exist in ...
biology Article What Makes a Successful Donor? Fecal Transplant from Anxious-Like Rats Does Not Prevent Spinal Cord Injury-Induced Dysbiosis Emma K. A. Schmidt 1 , Pamela J. F. Raposo 2,3 , Karen L. Madsen 4 , Keith K. Fenrich 1,2 , Gillian Kabarchuk 1 and Karim Fouad 1,2,3,*...
In addition, neuron-microglia interactions seem central in ALS pathogenesis, and CNS immune cells infiltration [79], as well as microglia and astrocyte activation, together with MN degeneration, are among hallmarks of the disease [58,80]. Cholesterol and oxysterol metabolism have been described as ...
En is also expressed in the posterior compartment, however posterior en expression does not depend on HH signalling indicating that the GRN downstream of HH differs between both compartments [136]. By contrast, HH synchronises cellular differentiation in the eye imaginal disk [137–139]. In the ...